Former EMBL staff scientist founds a start-up – DenovAI – for broader, faster and cheaper antibody discovery using advanced machine learning and computational biophysics Antibodies are an important tool in the human immune system’s arsenal against disease. They attach to bacteria, viruses, fungi, or toxins, marking them for destruction or removal from the body. It […]
Read MoreResearchers from the Ebisuya Group at EMBL Barcelona have used an unprecedented stem cell zoo to compare six different mammalian species and their developmental time. In humans, pregnancy lasts around nine months. In mice, only 20 days, and in rhinoceroses, as long as 17 months. Although many mammalian species go through the same stages during […]
Read More
Looking to learn more from genomics sequencing about DNA mutations and cancer, researchers applied a long-read approach to get a broader genomic view Just as a flashlight casts a broader beam than the brightest candle when walking along a darkened trail, so too does long-read genomic sequencing seem to clarify a broader genomic picture of […]
Read More
Pancreatic cancer is one of the most lethal cancers due to its early local extension and metastatic behaviour. Some of the reasons for this high fatality rate are late diagnosis of the disease, especially since symptoms are unspecific and appear rather late, and limited therapeutic options. Researchers from the European Molecular Biology Laboratory (EMBL) in […]
Read More
We are one of the most medicated generations of humans to live on our planet. Cardiometabolic diseases like type 2 diabetes, obesity, and coronary artery disease continue to increase in prevalence and together constitute the highest cause of mortality worldwide. Affected people often have to take multiple daily medications for months or even years. Researchers […]
Read More
Tuberculosis is one of the top ten causes of death worldwide, infecting about one-quarter of the world’s population. Although it is treatable, the rise of multidrug-resistant tuberculosis poses a major threat to global health security, and has been declared by the World Health Organization as a global health emergency. Reduced access to diagnosis and treatment […]
Read More
Lama-Mini-Antikörper und ihre synthetischen Imitationen Die Fähigkeit von SARS-CoV-2, Zellen zu infizieren, hängt von den Wechselwirkungen zwischen dem viralen Spike-Protein und dem menschlichen Zelloberflächenprotein ACE2 ab. Damit sich das Virus an der Zelloberfläche festhaken kann, bindet das Spike-Protein ACE2 über drei fingerartige Vorsprünge, die so genannten Rezeptorbindungsdomänen (RBDs). Die Blockierung der RBDs hat daher das […]
Read More
Llama mini-antibodies and their synthetic imitations The ability of SARS-CoV-2 to infect cells depends on interactions between the viral spike protein and the human cell surface protein ACE2. To enable the virus to hook onto the cell surface, the spike protein binds ACE2 using three finger-like protrusions, called the receptor binding domains (RBDs). Blocking the […]
Read MoreResearchers from the European Molecular Biology Laboratory in Heidelberg and Stanford University have found the cause of dilated cardiomyopathy – a leading cause of heart failure – and identified a potential treatment for it: a drug already used to treat acne. The study was published on 8 September in Cell Reports. The original press release […]
Read More
An international team of scientists has uncovered how cells remove unwanted components from the nucleus following mitosis. The results, published in the journal Nature, stem from a fruitful collaboration between the European Molecular Biology Laboratory in Heidelberg and the Institute of Molecular Biotechnology in Vienna. The press release can be found here. The organisation of […]
Read More